In the comes, Cassandra is blind and has myasthenia gravis, a chronic autoimmune disorder in which communication between the nerves and muscle cells breakdown, resulting in muscle weakness, paralysis, and neurological deterioration. Madame Web is known as the "Creepy Clairvoyant." Cassandra Webb, aka the first Madame Web, made her debut in The Amazing Spider-Man #210 by Denny O'Neil, John Romita Jr., Joe Sinnott, Bob Sharen, and Jim Novak from 1980. Given the recent opening in the multiverse and the characters' Marvel Comics' origins stories, it wouldn't be surprising to learn both Madame Webs may come into play if the feature film comes to fruition. So which Madame Web will Dakota Johnson be playing in the upcoming film? While no one at MovieWeb is precognitive like the character, some pretty compelling clues help Marvel fans figure it out. Although Madame Web is a quasi-regular supporting character in Spider-Man stories, her biggest claim to fame is her recurring role in the '90s Spider-Man animated series, voiced by Joan Lee, Stan Lee's wife. However, Madame Web also has a much younger version a second-generation Spider-Woman named Julia Carpenter gains precognition powers after Cassandra is killed.
Some have assumed that Johnson will portray the sometimes elderly Cassandra Webb, who has an autoimmune disease known as myasthenia gravis, keeping her confined to a life-support system resembling a spider web.
Insiders say the character is supposed to be Sony's version of Doctor Strange.
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